| Arsenal FC v Tottenham Hotspur FC 26/09/2021 | £7.50 | |
| Crystal Palace FC v Brighton & Hove Albion FC 27/09/2021 | £7.50 | |
| Crystal Palace FC v Brighton & Hove Albion FC 27/09/2021 | £7.50 | |
| Cardiff City FC v West Bromwich Albion FC 28/09/2021 | £7.50 | |
| Cardiff City FC v West Bromwich Albion FC 28/09/2021 | £6.00 | |
| Huddersfield Town FC v Blackburn Rovers FC 28/09/2021 | £8.50 | |
| Queens Park Rangers FC v Birmingham City FC 28/09/2021 | £7.50 | |
| Burton Albion FC v Portsmouth FC 28/09/2021 | £7.50 | |
| Morecambe FC v Lincoln City FC 28/09/2021 | £8.50 | |
| Plymouth Argyle FC v Crewe Alexandra FC 28/09/2021 | £7.50 | |
| Sunderland FC v Cheltenham Town FC 28/09/2021 | £7.50 | |
| Wigan Athletic FC v Sheffield Wednesday FC 28/09/2021 | £7.50 |