| West Bromwich Albion FC v Millwall FC 11/09/2021 | £7.50 | |
| Leeds United FC v Liverpool FC 12/09/2021 | £7.50 | |
| Everton FC v Burnley FC 13/09/2021 | £7.50 | |
| Blackpool FC v Huddersfield Town FC 14/09/2021 | £7.50 | |
| AFC Bournemouth v Queens Park Rangers FC 14/09/2021 | £5.99 | |
| West Bromwich Albion FC v Derby County FC 14/09/2021 | £7.50 | |
| Newport County AFC v Northampton Town FC 14/09/2021 | £7.50 | |
| Swansea City FC v Millwall FC 15/09/2021 | £8.50 | |
| Manchester City FC v RB Leipzig 15/09/2021 | £7.50 | |
| Leicester City FC v SSC Napoli 16/09/2021 | £7.50 | |
| Cardiff City FC v AFC Bournemouth 18/09/2021 | £8.00 | |
| Huddersfield Town FC v Nottingham Forest FC 18/09/2021 | £8.50 |