| Manchester City FC v Burnley FC 16/10/2021 | £7.50 | |
| Norwich City FC v Brighton & Hove Albion FC 16/10/2021 | £7.50 | |
| Southampton FC v Leeds United FC 16/10/2021 | £7.50 | |
| Watford FC v Liverpool FC 16/10/2021 | £8.50 | |
| Newcastle United FC v Tottenham Hotspur FC 17/10/2021 | £17.99 | |
| Everton FC v West Ham United FC 17/10/2021 | £7.50 | |
| Swansea City FC v Cardiff City FC 17/10/2021 | £8.50 | |
| Arsenal FC v Crystal Palace FC 18/10/2021 | £7.50 | |
| Gillingham FC v Doncaster Rovers FC 19/10/2021 | £7.50 | |
| Barrow AFC v Scunthorpe United FC 19/10/2021 | £9.50 | |
| Newport County AFC v Carlisle United FC 19/10/2021 | £7.50 | |
| Sutton United v Swindon Town FC 19/10/2021 | £7.50 |