| Burnley FC v Tottenham Hotspur FC 27/10/2021 | £7.50 | |
| Leicester City FC v Brighton & Hove Albion FC 27/10/2021 | £7.50 | |
| Leicester City FC v Brighton & Hove Albion FC 27/10/2021 | £6.50 | |
| West Ham United FC v Manchester City FC 27/10/2021 | £7.50 | |
| Preston North End FC v Liverpool FC 27/10/2021 | £7.50 | |
| Barrow AFC v Rochdale FC 30/10/2021 | £12.50 | |
| Colchester United FC v Scunthorpe United FC 30/10/2021 | £7.50 | |
| Newport County AFC v Stevenage Borough FC 30/10/2021 | £7.50 | |
| Oldham Athletic FC v Swindon Town FC 30/10/2021 | £7.50 | |
| Cheltenham Town FC v Sheffield Wednesday FC 30/10/2021 | £7.50 | |
| Gillingham FC v Accrington Stanley FC 30/10/2021 | £7.50 | |
| Fulham FC v West Bromwich Albion FC 30/10/2021 | £8.50 |