| Hayes & Yeading United v Southport 19/02/2011 | View match | |
| Crawley Town FC v Southport 22/02/2011 | View match | |
| Bath City v Southport 26/02/2011 | View match | |
| Southport v Histon 01/03/2011 | View match | |
| Eastbourne Borough v Southport 05/03/2011 | View match | |
| Southport v Cambridge United FC 12/03/2011 | View match | |
| Southport v Barrow AFC 15/03/2011 | View match | |
| Rushden & Diamonds v Southport 19/03/2011 | View match | |
| Southport v Luton Town FC 26/03/2011 | View match | |
| Altrincham v Southport 29/03/2011 | View match | |
| Southport v Eastbourne Borough 02/04/2011 | View match | |
| Mansfield Town FC v Southport 05/04/2011 | View match |