| Hyde FC v Southport 27/08/2012 | View match | |
| Southport v AFC Telford Utd 01/09/2012 | View match | |
| Southport v Gateshead 04/09/2012 | View match | |
| Kidderminister Harriers v Southport 08/09/2012 | View match | |
| Southport v Ebbsfleet United 15/09/2012 | View match | |
| Newport County AFC v Southport 22/09/2012 | View match | |
| Southport v Stockport County FC 25/09/2012 | View match | |
| Luton Town FC v Southport 29/09/2012 | View match | |
| Southport v Nuneaton Borough 06/10/2012 | View match | |
| Barrow AFC v Southport 09/10/2012 | View match | |
| Woking FC v Southport 13/10/2012 | View match | |
| Southport v Hereford United 27/10/2012 | View match |