| Tottenham Hotspur FC v Brighton & Hove Albion FC 05/02/2022 | £8.00 | |
| Burton Albion FC v Sheffield Wednesday FC 05/02/2022 | £9.50 | |
| Rochdale FC v Carlisle United FC 05/02/2022 | £7.50 | |
| Swansea City FC v Blackburn Rovers FC 05/02/2022 | £8.50 | |
| Barrow AFC v Tranmere Rovers FC 05/02/2022 | £12.50 | |
| Swindon Town FC v Exeter City FC 05/02/2022 | £7.50 | |
| Nottingham Forest FC v Leicester City FC 06/02/2022 | £7.50 | |
| Gillingham FC v Cambridge United FC 08/02/2022 | £7.50 | |
| Sheffield Wednesday FC v Wigan Athletic FC 08/02/2022 | £7.50 | |
| Exeter City FC v Leyton Orient FC 08/02/2022 | £7.50 | |
| Luton Town FC v Barnsley FC 08/02/2022 | £7.50 | |
| Tranmere Rovers FC v Swindon Town FC 08/02/2022 | £8.50 |