| Huddersfield Town FC v Sheffield United FC 12/02/2022 | £7.50 | |
| Millwall FC v Cardiff City FC 12/02/2022 | £7.50 | |
| Barrow AFC v Stevenage Borough FC 12/02/2022 | £9.50 | |
| Newport County AFC v Oldham Athletic FC 12/02/2022 | £7.50 | |
| Rochdale FC v Harrogate Town 12/02/2022 | £7.50 | |
| Swindon Town FC v Scunthorpe United FC 12/02/2022 | £7.50 | |
| Swansea City FC v Bristol City FC 13/02/2022 | £8.50 | |
| Newcastle United FC v Aston Villa FC 13/02/2022 | £7.50 | |
| Leicester City FC v West Ham United FC 13/02/2022 | £7.50 | |
| Burnley FC v Liverpool FC 13/02/2022 | £7.50 | |
| Sheffield Wednesday FC v Rotherham United FC 13/02/2022 | £7.50 | |
| Manchester United FC v Brighton & Hove Albion FC 15/02/2022 | £7.50 |