| Swansea City FC v Luton Town FC 01/02/2022 | £8.50 | |
| Huddersfield Town FC v Derby County FC 02/02/2022 | £7.50 | |
| Manchester United FC v Middlesbrough FC 04/02/2022 | £7.50 | |
| Cambridge United FC v Luton Town FC 05/02/2022 | £7.50 | |
| Chelsea FC v Plymouth Argyle FC 05/02/2022 | £7.50 | |
| Crystal Palace FC v Hartlepool United 05/02/2022 | £7.50 | |
| Everton FC v Brentford FC 05/02/2022 | £7.50 | |
| Huddersfield Town FC v Barnsley FC 05/02/2022 | £7.50 | |
| Kidderminister Harriers v West Ham United FC 05/02/2022 | £8.50 | |
| Manchester City FC v Fulham FC 05/02/2022 | £7.50 | |
| Peterborough United FC v Queens Park Rangers FC 05/02/2022 | £6.50 | |
| Southampton FC v Coventry City FC 05/02/2022 | £7.50 |