| Barrow AFC v Port Vale FC 02/04/2022 | £7.50 | |
| Salford City v Port Vale FC 05/04/2022 | View match | |
| Port Vale FC v Oldham Athletic FC 09/04/2022 | View match | |
| Hartlepool United v Port Vale FC 15/04/2022 | View match | |
| Port Vale FC v Bristol Rovers FC 18/04/2022 | View match | |
| Walsall FC v Port Vale FC 23/04/2022 | View match | |
| Port Vale FC v Newport County AFC 02/05/2022 | View match | |
| Exeter City FC v Port Vale FC 07/05/2022 | View match | |
| Swindon Town FC v Port Vale FC 15/05/2022 | View match | |
| Port Vale FC v Swindon Town FC 19/05/2022 | View match | |
| Mansfield Town FC v Port Vale FC 28/05/2022 | View match | |
| Port Vale FC v Fleetwood Town FC 30/07/2022 | View match |