| Aldershot Town F.C v Southport 10/12/2005 | View match | |
| Southport v Morecambe FC 26/12/2005 | View match | |
| Morecambe FC v Southport 02/01/2006 | View match | |
| Southport v Dagenham & Redbridge 07/01/2006 | View match | |
| Southport v Scarborough FC 14/01/2006 | View match | |
| Stevenage Borough FC v Southport 21/01/2006 | View match | |
| York City FC v Southport 24/01/2006 | View match | |
| Southport v Kidderminister Harriers 28/01/2006 | View match | |
| Southport v Canvey Island 11/02/2006 | View match | |
| Cambridge United FC v Southport 18/02/2006 | View match | |
| Exeter City FC v Southport 04/03/2006 | View match | |
| Forest Green Rovers v Southport 11/03/2006 | View match |