| Woking FC v Southport 15/11/2005 | View match | |
| Southport v FC Halifax Town 19/11/2005 | View match | |
| Accrington Stanley FC v Southport 26/11/2005 | View match | |
| Aldershot Town F.C v Southport 10/12/2005 | View match | |
| Southport v Morecambe FC 26/12/2005 | View match | |
| Morecambe FC v Southport 02/01/2006 | View match | |
| Southport v Dagenham & Redbridge 07/01/2006 | View match | |
| Southport v Scarborough FC 14/01/2006 | View match | |
| Stevenage Borough FC v Southport 21/01/2006 | View match | |
| York City FC v Southport 24/01/2006 | View match | |
| Southport v Kidderminister Harriers 28/01/2006 | View match | |
| Southport v Canvey Island 11/02/2006 | View match |