| Barnsley FC v West Bromwich Albion FC 17/12/2021 | £7.50 | |
| Middlesbrough FC v AFC Bournemouth 18/12/2021 | £7.50 | |
| Rochdale FC v Newport County AFC 18/12/2021 | £7.50 | |
| Tranmere Rovers FC v Leyton Orient FC 18/12/2021 | £7.50 | |
| Leeds United FC v Arsenal FC 18/12/2021 | £7.50 | |
| Aston Villa FC v Burnley FC 18/12/2021 | £8.50 | |
| Plymouth Argyle FC v Charlton Athletic FC 18/12/2021 | £7.50 | |
| AFC Wimbledon FC v Portsmouth FC 18/12/2021 | £7.50 | |
| Sheffield Wednesday FC v Accrington Stanley FC 18/12/2021 | £7.50 | |
| Newcastle United FC v Manchester City FC 19/12/2021 | £9.50 | |
| Wolverhampton Wanderers FC v Chelsea FC 19/12/2021 | £7.50 | |
| Arsenal FC v Sunderland FC 21/12/2021 | £7.50 |