| Southport v Mansfield Town FC 20/08/1949 | View match | |
| Southport v Chester City FC 22/08/1949 | View match | |
| Stockport County FC v Southport 27/08/1949 | View match | |
| Chester City FC v Southport 31/08/1949 | View match | |
| Southport v Doncaster Rovers FC 03/09/1949 | View match | |
| Southport v Halifax Town A.F.C 05/09/1949 | View match | |
| Gateshead v Southport 10/09/1949 | View match | |
| Halifax Town A.F.C v Southport 12/09/1949 | View match | |
| Southport v Hartlepool United 17/09/1949 | View match | |
| Darlington FC v Southport 24/09/1949 | View match | |
| Tranmere Rovers FC v Southport 29/09/1949 | View match | |
| Southport v New Brighton 01/10/1949 | View match |