| New Brighton v Southport 02/10/1948 | View match | |
| Southport v Mansfield Town FC 09/10/1948 | View match | |
| Tranmere Rovers FC v Southport 16/10/1948 | View match | |
| Southport v Oldham Athletic FC 23/10/1948 | View match | |
| Accrington Stanley (1891) v Southport 30/10/1948 | View match | |
| Southport v Rotherham United FC 06/11/1948 | View match | |
| Hull City FC v Southport 13/11/1948 | View match | |
| Southport v Doncaster Rovers FC 20/11/1948 | View match | |
| Southport v Horden Colliery Welfare 27/11/1948 | View match | |
| Southport v York City FC 11/12/1948 | View match | |
| York City FC v Southport 18/12/1948 | View match | |
| Southport v Barrow 25/12/1948 | View match |