| Southampton FC v Derby County FC 16/01/2019 | £7.50 | |
| Southampton FC v Everton FC 19/01/2019 | £6.50 | |
| Arsenal FC v Southampton FC 24/02/2019 | £3.50 | |
| Manchester United FC v Southampton FC 02/03/2019 | £6.50 | |
| Southampton FC v Tottenham Hotspur FC 09/03/2019 | £9.50 | |
| Brighton & Hove Albion FC v Southampton FC 30/03/2019 | £6.50 | |
| Southampton FC v Liverpool FC 05/04/2019 | £6.50 | |
| Southampton FC v AFC Bournemouth 27/04/2019 | £6.50 | |
| West Ham United FC v Southampton FC 04/05/2019 | £4.50 | |
| West Ham United FC v Southampton FC 04/05/2019 | £6.50 | |
| Southampton FC v Liverpool FC 17/08/2019 | £19.99 | |
| Brighton & Hove Albion FC v Southampton FC 24/08/2019 | £6.75 |