| Southampton FC v Tranmere Rovers FC 17/02/2001 | £4.00 | |
| Tranmere Rovers FC v Southampton FC 20/02/2001 | £6.00 | |
| Manchester City FC v Southampton FC 03/03/2001 | £4.00 | |
| Southampton FC v Everton FC 17/03/2001 | £5.00 | |
| Southampton FC v Ipswich Town FC 02/04/2001 | £4.00 | |
| Southampton FC v Ipswich Town FC 02/04/2001 | £4.50 | |
| Southampton FC v Ipswich Town FC 02/04/2001 | £6.50 | |
| Aston Villa FC v Southampton FC 21/04/2001 | £3.00 | |
| Aston Villa FC v Southampton FC 21/04/2001 | £2.00 | |
| Southampton FC v Sunderland FC 28/04/2001 | £2.50 | |
| Southampton FC v Sunderland FC 28/04/2001 | £4.50 | |
| West Ham United FC v Southampton FC 05/05/2001 | £5.00 |