| Torquay United FC v Southampton FC 15/01/1980 | View match | |
| Southampton FC v Manchester City FC 19/01/1980 | £3.00 | |
| Southampton FC v Luton Town FC 25/01/1980 | View match | |
| Tottenham Hotspur FC v Southampton FC 02/02/1980 | £3.50 | |
| Tottenham Hotspur FC v Southampton FC 02/02/1980 | £3.50 | |
| Tottenham Hotspur FC v Southampton FC 02/02/1980 | £3.50 | |
| Southampton FC v Brighton & Hove Albion FC 09/02/1980 | £3.50 | |
| Southampton FC v Brighton & Hove Albion FC 09/02/1980 | £3.50 | |
| Derby County FC v Southampton FC 16/02/1980 | View match | |
| Poole Town v Southampton FC 19/02/1980 | View match | |
| Coventry City FC v Southampton FC 23/02/1980 | View match | |
| Southampton FC v West Bromwich Albion FC 01/03/1980 | View match |