| Birmingham City FC v Southampton FC 23/10/1965 | £5.00 | |
| Southampton FC v Leyton Orient FC 30/10/1965 | £7.50 | |
| Southampton FC v Leyton Orient FC 30/10/1965 | £7.50 | |
| Middlesbrough FC v Southampton FC 06/11/1965 | View match | |
| Southampton FC v Huddersfield Town FC 13/11/1965 | View match | |
| Crystal Palace FC v Southampton FC 20/11/1965 | View match | |
| Southampton FC v Preston North End FC 27/11/1965 | £7.50 | |
| Southampton FC v Preston North End FC 27/11/1965 | £7.50 | |
| Charlton Athletic FC v Southampton FC 04/12/1965 | View match | |
| Southampton FC v Plymouth Argyle FC 11/12/1965 | £8.50 | |
| Ipswich Town FC v Southampton FC 18/12/1965 | View match | |
| Cardiff City FC v Southampton FC 27/12/1965 | View match |