| Southampton FC v Huddersfield Town FC 13/11/1965 | View match | |
| Crystal Palace FC v Southampton FC 20/11/1965 | View match | |
| Southampton FC v Preston North End FC 27/11/1965 | £7.50 | |
| Southampton FC v Preston North End FC 27/11/1965 | £7.50 | |
| Charlton Athletic FC v Southampton FC 04/12/1965 | View match | |
| Southampton FC v Plymouth Argyle FC 11/12/1965 | £8.50 | |
| Ipswich Town FC v Southampton FC 18/12/1965 | View match | |
| Cardiff City FC v Southampton FC 27/12/1965 | View match | |
| Southampton FC v Bolton Wanderers FC 01/01/1966 | View match | |
| Huddersfield Town FC v Southampton FC 08/01/1966 | View match | |
| Hull City FC v Southampton FC 22/01/1966 | View match | |
| Southampton FC v Derby County FC 29/01/1966 | View match |