| Luton Town FC v West Bromwich Albion FC 19/02/2022 | £7.50 | |
| Stoke City FC v Luton Town FC 23/02/2022 | View match | |
| Luton Town FC v Derby County FC 26/02/2022 | £7.50 | |
| Luton Town FC v Chelsea FC 02/03/2022 | View match | |
| Middlesbrough FC v Luton Town FC 05/03/2022 | View match | |
| Coventry City FC v Luton Town FC 08/03/2022 | £7.50 | |
| Luton Town FC v Queens Park Rangers FC 13/03/2022 | £7.50 | |
| Luton Town FC v Preston North End FC 16/03/2022 | View match | |
| Hull City FC v Luton Town FC 19/03/2022 | £7.50 | |
| Luton Town FC v Millwall FC 02/04/2022 | £7.50 | |
| Peterborough United FC v Luton Town FC 05/04/2022 | £7.50 | |
| Huddersfield Town FC v Luton Town FC 11/04/2022 | £7.50 |