| Luton Town FC v Coventry City FC 29/09/2021 | £7.50 | |
| Luton Town FC v Huddersfield Town FC 02/10/2021 | View match | |
| Millwall FC v Luton Town FC 16/10/2021 | View match | |
| Derby County FC v Luton Town FC 19/10/2021 | View match | |
| Luton Town FC v Hull City FC 23/10/2021 | £9.00 | |
| Preston North End FC v Luton Town FC 30/10/2021 | View match | |
| Luton Town FC v Middlesbrough FC 02/11/2021 | £7.50 | |
| Luton Town FC v Stoke City FC 06/11/2021 | £7.50 | |
| Queens Park Rangers FC v Luton Town FC 19/11/2021 | View match | |
| Nottingham Forest FC v Luton Town FC 23/11/2021 | View match | |
| Luton Town FC v Cardiff City FC 27/11/2021 | ||
| Blackpool FC v Luton Town FC 04/12/2021 | View match |