| Luton Town FC v Fulham FC 11/12/2021 | £7.50 | |
| Luton Town FC v Bristol City FC 26/12/2021 | View match | |
| Luton Town FC v Harrogate Town 09/01/2022 | £7.50 | |
| Luton Town FC v AFC Bournemouth 15/01/2022 | £7.50 | |
| Reading FC v Luton Town FC 19/01/2022 | View match | |
| Sheffield United FC v Luton Town FC 22/01/2022 | View match | |
| Luton Town FC v Bristol City FC 25/01/2022 | View match | |
| Luton Town FC v Blackburn Rovers FC 29/01/2022 | £7.50 | |
| Swansea City FC v Luton Town FC 01/02/2022 | £8.50 | |
| Cambridge United FC v Luton Town FC 05/02/2022 | £7.50 | |
| Luton Town FC v Barnsley FC 08/02/2022 | £7.50 | |
| Birmingham City FC v Luton Town FC 12/02/2022 | View match |