| Tranmere Rovers FC v Port Vale FC 19/02/2022 | £7.50 | |
| Newport County AFC v Tranmere Rovers FC 26/02/2022 | £8.50 | |
| Northampton Town FC v Tranmere Rovers FC 05/03/2022 | View match | |
| Tranmere Rovers FC v Mansfield Town FC 11/03/2022 | View match | |
| Tranmere Rovers FC v Harrogate Town 15/03/2022 | View match | |
| Sutton United v Tranmere Rovers FC 19/03/2022 | View match | |
| Colchester United FC v Tranmere Rovers FC 26/03/2022 | View match | |
| Tranmere Rovers FC v Carlisle United FC 02/04/2022 | View match | |
| Tranmere Rovers FC v Bristol Rovers FC 09/04/2022 | View match | |
| Bradford City FC v Tranmere Rovers FC 15/04/2022 | View match | |
| Tranmere Rovers FC v Exeter City FC 18/04/2022 | £7.50 | |
| Stevenage Borough FC v Tranmere Rovers FC 23/04/2022 | View match |