| Southampton FC v Nottingham Forest FC 10/09/2011 | View match | |
| Southampton FC v Birmingham City FC 18/09/2011 | £7.00 | |
| Southampton FC v Preston North End FC 21/09/2011 | £7.00 | |
| Burnley FC v Southampton FC 24/09/2011 | £5.50 | |
| Cardiff City FC v Southampton FC 28/09/2011 | £5.50 | |
| Southampton FC v Watford FC 01/10/2011 | £7.00 | |
| Derby County FC v Southampton FC 15/10/2011 | View match | |
| Southampton FC v West Ham United FC 18/10/2011 | £7.50 | |
| Reading FC v Southampton FC 22/10/2011 | View match | |
| Crystal Palace FC v Southampton FC 25/10/2011 | £5.50 | |
| Southampton FC v Middlesbrough FC 29/10/2011 | £7.50 | |
| Southampton FC v Peterborough United FC 01/11/2011 | £7.00 |