| Dagenham & Redbridge v Southampton FC 03/01/2011 | View match | |
| Southampton FC v Blackpool FC 08/01/2011 | View match | |
| Oldham Athletic FC v Southampton FC 11/01/2011 | View match | |
| Southampton FC v Notts County FC 15/01/2011 | £5.50 | |
| Tranmere Rovers FC v Southampton FC 22/01/2011 | View match | |
| Southampton FC v Manchester United FC 29/01/2011 | £5.50 | |
| Exeter City FC v Southampton FC 01/02/2011 | View match | |
| Peterborough United FC v Southampton FC 05/02/2011 | View match | |
| Southampton FC v Carlisle United FC 12/02/2011 | View match | |
| Hartlepool United v Southampton FC 22/02/2011 | View match | |
| Southampton FC v Swindon Town FC 26/02/2011 | £5.50 | |
| Walsall FC v Southampton FC 01/03/2011 | View match |