| Southampton FC v Swansea Town 02/09/1961 | View match | |
| Southampton FC v Walsall FC 06/09/1961 | View match | |
| Bury FC v Southampton FC 09/09/1961 | View match | |
| Southampton FC v Rochdale FC 13/09/1961 | View match | |
| Luton Town FC v Southampton FC 16/09/1961 | View match | |
| Walsall FC v Southampton FC 19/09/1961 | View match | |
| Southampton FC v Newcastle United FC 23/09/1961 | £7.50 | |
| Rochdale FC v Southampton FC 27/09/1961 | View match | |
| Middlesbrough FC v Southampton FC 30/09/1961 | View match | |
| Southampton FC v Brighton & Hove Albion FC 07/10/1961 | View match | |
| Scunthorpe United FC v Southampton FC 13/10/1961 | View match | |
| Southampton FC v Preston North End FC 18/10/1961 | View match |