| Leeds United FC v Southampton FC 02/04/2022 | £7.50 | |
| Liverpool FC v Watford FC 02/04/2022 | £7.50 | |
| Burnley FC v Manchester City FC 02/04/2022 | £9.50 | |
| Chelsea FC v Brentford FC 02/04/2022 | £8.50 | |
| Sheffield Wednesday FC v AFC Wimbledon FC 02/04/2022 | £7.50 | |
| West Ham United FC v Everton FC 03/04/2022 | £7.50 | |
| Birmingham City FC v West Bromwich Albion FC 03/04/2022 | £7.50 | |
| Crystal Palace FC v Arsenal FC 04/04/2022 | £7.50 | |
| Preston North End FC v Blackpool FC 05/04/2022 | £7.50 | |
| Peterborough United FC v Luton Town FC 05/04/2022 | £7.50 | |
| AFC Wimbledon FC v Charlton Athletic FC 05/04/2022 | £7.50 | |
| Leicester City FC v PSV Eindhoven 07/04/2022 | £7.50 |