| Wigan Borough v Ashington 01/04/1922 | View match | |
| South Shields AFC v Blackpool FC 01/04/1922 | View match | |
| Stalybridge Celtic v Barrow 01/04/1922 | View match | |
| Nelson v Halifax Town A.F.C 01/04/1922 | View match | |
| Johnstone v Arbroath FC 01/04/1922 | View match | |
| Boness United v Vale Of Leven 01/04/1922 | View match | |
| Kings Park v Forfar Athletic FC 01/04/1922 | View match | |
| Stenhousemuir FC v St Bernard`s 01/04/1922 | View match | |
| Heart Of Midlothian (Hearts) v Partick Thistle FC 01/04/1922 | View match | |
| Kilmarnock FC v Hamilton Academicals 01/04/1922 | View match | |
| Clyde v Dumbarton 01/04/1922 | View match | |
| St Johnstone FC v East Fife FC 01/04/1922 | View match |