| Hamilton Academicals v Heart Of Midlothian (Hearts) 17/08/1921 | View match | |
| Dundee v Airdrieonians (Old) 17/08/1921 | View match | |
| Queens Park FC v Ayr United FC 17/08/1921 | View match | |
| Morton FC v Motherwell FC 17/08/1921 | View match | |
| Kings Park v East Stirlingshire FC 20/08/1921 | View match | |
| Arbroath FC v Johnstone 20/08/1921 | View match | |
| Third Lanark v Hamilton Academicals 20/08/1921 | View match | |
| Armadale v St Bernard`s 20/08/1921 | View match | |
| East Fife FC v Bathgate 20/08/1921 | View match | |
| Motherwell FC v Raith Rovers FC 20/08/1921 | View match | |
| Falkirk FC v Dundee 20/08/1921 | View match | |
| Cowdenbeath FC v Lochgelly United 20/08/1921 | View match |