| Port Vale FC v Southend United FC 10/11/1980 | View match | |
| Doncaster Rovers FC v Port Vale FC 15/11/1980 | View match | |
| Port Vale FC v Bradford City FC 22/11/1980 | View match | |
| Port Vale FC v Crewe Alexandra FC 05/12/1980 | View match | |
| Burnley FC v Port Vale FC 13/12/1980 | View match | |
| Port Vale FC v Burnley FC 16/12/1980 | View match | |
| Halifax Town A.F.C v Port Vale FC 20/12/1980 | View match | |
| Port Vale FC v Lincoln City FC 26/12/1980 | View match | |
| Northampton Town FC v Port Vale FC 27/12/1980 | View match | |
| Port Vale FC v Enfield 03/01/1981 | View match | |
| Enfield v Port Vale FC 06/01/1981 | View match | |
| Hartlepool United v Port Vale FC 10/01/1981 | View match |