| Port Vale FC v Workington 02/03/1959 | View match | |
| Port Vale FC v Barrow 07/03/1959 | View match | |
| Carlisle United FC v Port Vale FC 14/03/1959 | View match | |
| Coventry City FC v Port Vale FC 16/03/1959 | View match | |
| Port Vale FC v Gillingham FC 21/03/1959 | View match | |
| Crewe Alexandra FC v Port Vale FC 27/03/1959 | View match | |
| Exeter City FC v Port Vale FC 28/03/1959 | View match | |
| Port Vale FC v Crewe Alexandra FC 30/03/1959 | £12.50 | |
| Port Vale FC v Coventry City FC 04/04/1959 | View match | |
| Shrewsbury Town FC v Port Vale FC 11/04/1959 | View match | |
| York City FC v Port Vale FC 15/04/1959 | View match | |
| Port Vale FC v Darlington FC 18/04/1959 | View match |