| Watford FC v Tottenham Hotspur FC 01/01/2022 | £7.50 | |
| Leicester City FC v Watford FC 08/01/2022 | £8.50 | |
| Watford FC v Brighton & Hove Albion FC 12/02/2022 | £9.50 | |
| Aston Villa FC v Watford FC 19/02/2022 | £7.50 | |
| Manchester United FC v Watford FC 26/02/2022 | £7.50 | |
| Watford FC v Arsenal FC 06/03/2022 | £7.50 | |
| Liverpool FC v Watford FC 02/04/2022 | £7.50 | |
| Watford FC v Brentford FC 16/04/2022 | £7.50 | |
| Manchester City FC v Watford FC 23/04/2022 | £7.50 | |
| Watford FC v Burnley FC 30/04/2022 | £7.50 | |
| Watford FC v Everton FC 11/05/2022 | £8.50 | |
| Chelsea FC v Watford FC 22/05/2022 | £7.50 |