| St Mirren FC v Dundee United FC 11/09/2021 | View match | |
| Hibernian FC v St Mirren FC 18/09/2021 | View match | |
| St Mirren FC v Aberdeen FC 26/09/2021 | View match | |
| Livingston FC v St Mirren FC 02/10/2021 | View match | |
| Ross County FC v St Mirren FC 16/10/2021 | View match | |
| St Mirren FC v Rangers (Glasgow) FC 24/10/2021 | View match | |
| Motherwell FC v St Mirren FC 27/10/2021 | View match | |
| St Mirren FC v Dundee 30/10/2021 | View match | |
| St Johnstone FC v St Mirren FC 06/11/2021 | View match | |
| St Mirren FC v Livingston FC 20/11/2021 | View match | |
| Heart Of Midlothian (Hearts) v St Mirren FC 27/11/2021 | View match | |
| St Mirren FC v Ross County FC 01/12/2021 | View match |