| Southampton FC v Watford FC 26/08/1980 | £3.00 | |
| Southampton FC v Brighton & Hove Albion FC 06/09/1980 | £3.00 | |
| Southampton FC v Brighton & Hove Albion FC 06/09/1980 | £2.00 | |
| Southampton FC v Liverpool FC 20/09/1980 | £2.50 | |
| Southampton FC v Wolverhampton Wanderers FC 07/10/1980 | £1.50 | |
| Southampton FC v Stoke City FC 11/10/1980 | £2.00 | |
| Southampton FC v Ipswich Town FC 08/11/1980 | £2.00 | |
| Southampton FC v Leeds United FC 22/11/1980 | £2.50 | |
| Manchester United FC v Southampton FC 29/11/1980 | £2.50 | |
| Southampton FC v Coventry City FC 06/12/1980 | £2.50 | |
| Southampton FC v Crystal Palace FC 20/12/1980 | £2.00 | |
| Tottenham Hotspur FC v Southampton FC 26/12/1980 | £3.00 |