| Southampton FC v Arsenal FC 26/12/2015 | £6.50 | |
| West Ham United FC v Southampton FC 28/12/2015 | £11.50 | |
| Southampton FC v West Bromwich Albion FC 16/01/2016 | £4.50 | |
| Southampton FC v West Bromwich Albion FC 16/01/2016 | £4.99 | |
| Manchester United FC v Southampton FC 23/01/2016 | £5.00 | |
| Arsenal FC v Southampton FC 02/02/2016 | £7.00 | |
| Arsenal FC v Southampton FC 02/02/2016 | £6.00 | |
| AFC Bournemouth v Southampton FC 01/03/2016 | £6.00 | |
| Southampton FC v Liverpool FC 20/03/2016 | £5.50 | |
| Southampton FC v Manchester City FC 01/05/2016 | £4.00 | |
| Southampton FC v Manchester City FC 01/05/2016 | £6.00 | |
| Tottenham Hotspur FC v Southampton FC 08/05/2016 | £6.50 |