| Southampton FC v Brighton & Hove Albion FC 02/04/1945 | View match | |
| Southampton FC v Brentford FC 14/04/1945 | View match | |
| West Ham United FC v Southampton FC 21/04/1945 | View match | |
| Plymouth Argyle FC v Southampton FC 01/09/1945 | View match | |
| Portsmouth FC v Southampton FC 08/09/1945 | £85.00 | |
| Chelsea FC v Southampton FC 12/09/1945 | View match | |
| Southampton FC v Portsmouth FC 15/09/1945 | View match | |
| Southampton FC v Nottingham Forest FC 22/09/1945 | View match | |
| Watford FC v Southampton FC 22/09/1945 | View match | |
| Nottingham Forest FC v Southampton FC 29/09/1945 | View match | |
| Newport County v Southampton FC 06/10/1945 | View match | |
| Southampton FC v Newport County 13/10/1945 | View match |