| Southampton FC v Brighton & Hove Albion FC 02/01/2006 | View match | |
| Southampton FC v MK Dons (Milton Keynes Dons) 07/01/2006 | £3.70 | |
| Queens Park Rangers FC v Southampton FC 14/01/2006 | View match | |
| Southampton FC v Ipswich Town FC 21/01/2006 | View match | |
| Southampton FC v Crystal Palace FC 25/01/2006 | View match | |
| Leicester City FC v Southampton FC 28/01/2006 | £4.80 | |
| Plymouth Argyle FC v Southampton FC 31/01/2006 | View match | |
| Southampton FC v Derby County FC 04/02/2006 | View match | |
| Reading FC v Southampton FC 10/02/2006 | View match | |
| Southampton FC v Preston North End FC 15/02/2006 | £4.00 | |
| Southampton FC v Preston North End FC 15/02/2006 | £4.50 | |
| Southampton FC v Preston North End FC 15/02/2006 | £4.50 |