| Mansfield Town FC v Southampton FC 26/09/2000 | View match | |
| Southampton FC v Middlesbrough FC 30/09/2000 | £2.50 | |
| Southampton FC v Middlesbrough FC 30/09/2000 | £2.50 | |
| Everton FC v Southampton FC 14/10/2000 | View match | |
| Southampton FC v Manchester City FC 23/10/2000 | £3.00 | |
| Southampton FC v Manchester City FC 23/10/2000 | £5.00 | |
| Manchester United FC v Southampton FC 28/10/2000 | £3.00 | |
| Southampton FC v Coventry City FC 01/11/2000 | £3.00 | |
| Southampton FC v Coventry City FC 01/11/2000 | £3.50 | |
| Southampton FC v Chelsea FC 04/11/2000 | £4.50 | |
| Southampton FC v Chelsea FC 04/11/2000 | £3.00 | |
| Sunderland FC v Southampton FC 11/11/2000 | View match |