| Sheffield Wednesday FC v Gillingham FC 13/11/2021 | £7.50 | |
| Plymouth Argyle FC v Sheffield Wednesday FC 16/11/2021 | View match | |
| Accrington Stanley FC v Sheffield Wednesday FC 20/11/2021 | View match | |
| Sheffield Wednesday FC v MK Dons (Milton Keynes Dons) 23/11/2021 | £7.50 | |
| Sheffield Wednesday FC v Wycombe Wanderers FC 27/11/2021 | £7.50 | |
| Sheffield Wednesday FC v Hartlepool United 01/12/2021 | £7.50 | |
| Portsmouth FC v Sheffield Wednesday FC 07/12/2021 | £7.50 | |
| Crewe Alexandra FC v Sheffield Wednesday FC 11/12/2021 | View match | |
| Sheffield Wednesday FC v Accrington Stanley FC 18/12/2021 | £7.50 | |
| Sunderland FC v Sheffield Wednesday FC 30/12/2021 | £7.50 | |
| Shrewsbury Town FC v Sheffield Wednesday FC 02/01/2022 | £7.50 | |
| Sheffield Wednesday FC v Plymouth Argyle FC 15/01/2022 | £9.50 |