| Yeovil Town FC v Sheffield Wednesday FC 16/10/2010 | View match | |
| Sheffield Wednesday FC v AFC Bournemouth 23/10/2010 | £3.50 | |
| Charlton Athletic FC v Sheffield Wednesday FC 30/10/2010 | View match | |
| Sheffield Wednesday FC v Huddersfield Town FC 02/11/2010 | £3.50 | |
| Southport v Sheffield Wednesday FC 07/11/2010 | View match | |
| Sheffield Wednesday FC v Hartlepool United 10/11/2010 | £4.10 | |
| Sheffield Wednesday FC v Rochdale FC 13/11/2010 | £3.50 | |
| MK Dons (Milton Keynes Dons) v Sheffield Wednesday FC 20/11/2010 | View match | |
| Sheffield Wednesday FC v Walsall FC 23/11/2010 | View match | |
| Sheffield Wednesday FC v Northampton Town FC 27/11/2010 | £3.50 | |
| Swindon Town FC v Sheffield Wednesday FC 04/12/2010 | View match | |
| Sheffield Wednesday FC v Bristol Rovers FC 11/12/2010 | £2.50 |