| Chelsea FC v Everton FC 04/12/2010 | £7.00 | |
| Ipswich Town FC v Swansea City FC 04/12/2010 | £5.50 | |
| Wigan Athletic FC v Stoke City FC 04/12/2010 | £5.50 | |
| West Bromwich Albion FC v Newcastle United FC 05/12/2010 | £6.50 | |
| Liverpool FC v Aston Villa FC 06/12/2010 | £5.50 | |
| Manchester United FC v Valencia CF 07/12/2010 | £5.50 | |
| Twente Enschende v Tottenham Hotspur FC 07/12/2010 | £12.50 | |
| Arsenal FC v FK Partizan Belgrade 08/12/2010 | £5.50 | |
| Luton Town FC v Charlton Athletic FC 09/12/2010 | £15.00 | |
| Huddersfield Town FC v Brighton & Hove Albion FC 11/12/2010 | £7.50 | |
| Sheffield Wednesday FC v Bristol Rovers FC 11/12/2010 | £2.50 | |
| Southampton FC v Brentford FC 11/12/2010 | £5.50 |