| South Shields AFC v Bury FC 09/09/1922 | View match | |
| Wigan Borough v Crewe Alexandra FC 09/09/1922 | View match | |
| Nelson v Stalybridge Celtic 09/09/1922 | View match | |
| Durham City v Grimsby Town FC 09/09/1922 | View match | |
| Armadale v Bathgate 09/09/1922 | View match | |
| East Fife FC v Stenhousemuir FC 09/09/1922 | View match | |
| Johnstone v Queens Park FC 09/09/1922 | View match | |
| Falkirk FC v Rangers (Glasgow) FC 09/09/1922 | View match | |
| Motherwell FC v Dundee 09/09/1922 | View match | |
| Forfar Athletic FC v Boness United 09/09/1922 | View match | |
| Heart Of Midlothian (Hearts) v Albion Rovers FC 09/09/1922 | View match | |
| Kilmarnock FC v Clyde 09/09/1922 | View match |