| Nelson v Barrow 17/04/1922 | View match | |
| Wigan Borough v Wrexham FC 17/04/1922 | View match | |
| Chesterfield FC v Tranmere Rovers FC 17/04/1922 | View match | |
| Stoke v Blackpool FC 17/04/1922 | View match | |
| The Wednesday v Hull City FC 17/04/1922 | View match | |
| Clapton Orient v West Ham United FC 17/04/1922 | View match | |
| Rotherham County v Notts County FC 17/04/1922 | View match | |
| Watford FC v Bristol Rovers FC 17/04/1922 | View match | |
| Reading FC v Charlton Athletic FC 17/04/1922 | View match | |
| Liverpool FC v Burnley FC 17/04/1922 | View match | |
| Bristol City FC v Coventry City FC 17/04/1922 | View match | |
| Cardiff City FC v Blackburn Rovers FC 17/04/1922 | View match |