| Swindon Town FC v Reading FC 17/10/1959 | View match | |
| Reading FC v Tottenham Hotspur FC 21/10/1959 | View match | |
| Reading FC v York City FC 24/10/1959 | View match | |
| West Ham United FC v Reading FC 26/10/1959 | View match | |
| Bournemouth & Boscombe v Reading FC 31/10/1959 | View match | |
| Norwich City FC v Reading FC 14/11/1959 | View match | |
| Reading FC v Norwich City FC 18/11/1959 | View match | |
| Reading FC v Grimsby Town FC 21/11/1959 | View match | |
| Wrexham FC v Reading FC 28/11/1959 | View match | |
| Reading FC v Kings Lynn Town 05/12/1959 | View match | |
| Reading FC v Coventry City FC 12/12/1959 | View match | |
| Port Vale FC v Reading FC 19/12/1959 | View match |