| Norwich City FC v Port Vale FC 08/10/1949 | View match | |
| Port Vale FC v Newport County 15/10/1949 | View match | |
| Bristol City FC v Port Vale FC 22/10/1949 | View match | |
| Port Vale FC v Brighton & Hove Albion FC 29/10/1949 | View match | |
| Walsall FC v Port Vale FC 05/11/1949 | View match | |
| Port Vale FC v Millwall FC 12/11/1949 | View match | |
| Port Vale FC v Millwall FC 12/11/1949 | View match | |
| Swindon Town FC v Port Vale FC 19/11/1949 | View match | |
| Port Vale FC v Wealdstone 26/11/1949 | View match | |
| Aldershot F.C v Port Vale FC 03/12/1949 | View match | |
| Port Vale FC v Tranmere Rovers FC 10/12/1949 | View match | |
| Bristol Rovers FC v Port Vale FC 17/12/1949 | View match |