| Morecambe FC v Doncaster Rovers FC 02/01/2022 | View match | |
| Tottenham Hotspur FC v Morecambe FC 09/01/2022 | View match | |
| AFC Wimbledon FC v Morecambe FC 15/01/2022 | £7.50 | |
| Morecambe FC v Wigan Athletic FC 18/01/2022 | View match | |
| Morecambe FC v Wycombe Wanderers FC 22/01/2022 | View match | |
| Accrington Stanley FC v Morecambe FC 29/01/2022 | View match | |
| Sheffield Wednesday FC v Morecambe FC 01/02/2022 | £7.50 | |
| Morecambe FC v Bolton Wanderers FC 05/02/2022 | View match | |
| Lincoln City FC v Morecambe FC 08/02/2022 | View match | |
| Morecambe FC v Gillingham FC 12/02/2022 | View match | |
| Rotherham United FC v Morecambe FC 22/02/2022 | View match | |
| Morecambe FC v Ipswich Town FC 26/02/2022 | View match |