| Swansea Town v Leyton Orient FC 04/03/1961 | View match | |
| Leyton Orient FC v Plymouth Argyle FC 07/03/1961 | £7.00 | |
| Leyton Orient FC v Luton Town FC 11/03/1961 | View match | |
| Leyton Orient FC v Middlesbrough FC 14/03/1961 | £6.99 | |
| Charlton Athletic FC v Leyton Orient FC 18/03/1961 | View match | |
| Leyton Orient FC v Huddersfield Town FC 21/03/1961 | £6.50 | |
| Leyton Orient FC v Portsmouth FC 25/03/1961 | View match | |
| Leyton Orient FC v Southampton FC 29/03/1961 | £7.00 | |
| Plymouth Argyle FC v Leyton Orient FC 01/04/1961 | View match | |
| Southampton FC v Leyton Orient FC 03/04/1961 | £6.99 | |
| Leyton Orient FC v Sunderland FC 08/04/1961 | View match | |
| Leyton Orient FC v Stoke City FC 10/04/1961 | View match |