| AFC Wimbledon FC v Leyton Orient FC 08/11/2022 | View match | |
| Harrogate Town v Leyton Orient FC 12/11/2022 | £8.00 | |
| Stockport County FC v Leyton Orient FC 19/11/2022 | ||
| Leyton Orient FC v Bradford City FC 03/12/2022 | View match | |
| Leyton Orient FC v Sutton United 17/12/2022 | View match | |
| Leyton Orient FC v Stevenage Borough FC 27/12/2022 | View match | |
| Newport County AFC v Leyton Orient FC 30/12/2022 | £8.00 | |
| Northampton Town FC v Leyton Orient FC 02/01/2023 | £8.00 | |
| Leyton Orient FC v Doncaster Rovers FC 07/01/2023 | View match | |
| Leyton Orient FC v Barrow AFC 14/01/2023 | View match | |
| Stevenage Borough FC v Leyton Orient FC 21/01/2023 | £8.00 | |
| Tranmere Rovers FC v Leyton Orient FC 28/01/2023 | £8.00 |