| Leyton Orient FC v Chester City FC 06/12/2005 | View match | |
| Leyton Orient FC v Bury FC 10/12/2005 | View match | |
| Rochdale FC v Leyton Orient FC 17/12/2005 | View match | |
| Leyton Orient FC v Rushden & Diamonds 26/12/2005 | View match | |
| Wycombe Wanderers FC v Leyton Orient FC 29/12/2005 | View match | |
| Leyton Orient FC v Notts County FC 31/12/2005 | View match | |
| Boston United v Leyton Orient FC 02/01/2006 | View match | |
| Fulham FC v Leyton Orient FC 08/01/2006 | £8.50 | |
| Leyton Orient FC v Northampton Town FC 14/01/2006 | View match | |
| Wrexham FC v Leyton Orient FC 21/01/2006 | View match | |
| Charlton Athletic FC v Leyton Orient FC 28/01/2006 | £4.60 | |
| Bristol Rovers FC v Leyton Orient FC 31/01/2006 | View match |