| Clyde v Queens Park FC 08/10/1921 | View match | |
| Aberdeen FC v Clyde 15/10/1921 | View match | |
| Clyde v Clydebank FC (Old) 22/10/1921 | View match | |
| Raith Rovers FC v Clyde 29/10/1921 | View match | |
| Hibernian FC v Clyde 05/11/1921 | View match | |
| Hibernian FC v Clyde 05/11/1921 | View match | |
| Clyde v Falkirk FC 12/11/1921 | View match | |
| Dumbarton v Clyde 19/11/1921 | View match | |
| Clyde v Albion Rovers FC 26/11/1921 | View match | |
| Dundee v Clyde 03/12/1921 | View match | |
| Clyde v Hamilton Academicals 10/12/1921 | View match | |
| Partick Thistle FC v Clyde 17/12/1921 | View match |