| East Fife FC v Clyde 05/02/2022 | View match | |
| Clyde v Dumbarton 12/02/2022 | View match | |
| Montrose FC v Clyde 19/02/2022 | View match | |
| Airdrieonians (Old) v Clyde 26/02/2022 | View match | |
| Clyde v Falkirk FC 05/03/2022 | View match | |
| Cove Rangers v Clyde 12/03/2022 | View match | |
| Clyde v East Fife FC 19/03/2022 | View match | |
| Queens Park FC v Clyde 26/03/2022 | View match | |
| Clyde v Peterhead 02/04/2022 | View match | |
| Alloa Athletic FC v Clyde 09/04/2022 | View match | |
| Clyde v Montrose FC 16/04/2022 | View match | |
| Clyde v Airdrieonians (Old) 23/04/2022 | View match |